Listing 23 Results Apical Basolateral Membrane

Apical–basal polarity and the control of epithelial form …

2 weeks ago WEB Apr 19, 2022  · Although the disease mechanisms are still under debate, mislocalization of basolateral proteins to apical membranes and vice versa also occurs in polycystic kidney disease, characterized by ...

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Apical–basal polarity and the control of epithelial …

1 week ago WEB Apr 19, 2022  · This apical–basal polarization underlies all aspects of epithelial biology (Fig. 1). The function of epithelia as barriers to fluids and pathogens depends on the correct …

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Role of membrane traffic in the generation of epithelial …

6 days ago WEB Epithelial cells have a pronounced apical–basolateral axis of asymmetry that is composed of functionally and morphologically distinct membrane domains ().The establishment of …

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Trafficking to the Apical and Basolateral Membranes in …

2 days ago WEB Mar 20, 2014  · Basolateral Sorting Signals. Basolateral sorting of both soluble secreted proteins and integral membrane proteins is directed primarily by signals embedded …

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The biophysical and biochemical polarization of the …

5 days ago WEB Feb 8, 2024  · Epithelial cell polarization is an essential biological process, serving many physiological roles including tissue morphogenesis and wound healing. A defining …

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New insights into apical-basal polarization in epithelia

6 days ago WEB Feb 1, 2020  · The localization of Par6–aPKC to the apical membrane is mediated by physical interactions with Par3, the active GTP-bound version of Cdc42, and Crumbs …

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Molecular Mechanisms of Apical and Basolateral Sorting …

1 week ago WEB Nov 27, 2020  · Selective retention at the apical or basolateral membrane may be achieved through interaction with a specialized cytoskeleton. For example, ankyrin G …

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Trafficking to the apical and basolateral membranes in …

1 week ago WEB Jul 1, 2014  · This review summarizes the current understanding of apical and basolateral trafficking routes in polarized epithelial cells and indicates that cell type-specific …

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The Role of Intestinal Permeability in Gastrointestinal …

2 days ago WEB Aug 26, 2021  · TEER measures the net flux of all ions (cations and anions) across the epithelium and reflects the contribution of the paracellular resistance (R para) that …

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Self-organization of apical membrane protein sorting in …

1 week ago WEB Apical sorting signals. The first site of apical membrane protein sorting is the trans Golgi network (TGN) [6–8].This was initially demonstrated by early studies showing that …

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[PDF] Apical–basal polarity and the control of epithelial form and ...

1 week ago WEB Apr 19, 2022  · Elucidating how distinct apical and basolateral compartments are established and maintained is essential to better understand the roles of apical–basal …

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Polarized sorting and trafficking in epithelial cells | Cell Research

1 week ago WEB Apr 24, 2012  · The polarized distribution of proteins and lipids at the surface membrane of epithelial cells results in the formation of an apical and a basolateral domain, which are …

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The subapical compartment: a traffic center in membrane polarity ...

2 weeks ago WEB May 1, 2004  · The apical and basolateral membranes are distinctly oriented with respect to microtubule polarity: microtubule plus ends face the basolateral membrane, whereas …

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Trafficking to the apical and basolateral membranes in polarized ...

6 days ago WEB Mar 20, 2014  · The Na,K-ATPase localizes to the apical membranes of cells of the retinal pigment epithelium (RPE) 113 – 116 and the choroid plexus. 117 – 120 Although these …

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Membrane Lipids in Epithelial Polarity: Sorting out the PIPs

1 week ago WEB May 31, 2022  · The development of cell polarity in epithelia, is critical for tissue morphogenesis and vectorial transport between the environment and the underlying …

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Epithelial polarity - Wikipedia

1 week ago WEB Epithelial polarity is one example of the cell polarity that is a fundamental feature of many types of cells. Epithelial cells feature distinct 'apical', 'lateral' and 'basal' plasma …

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Apicobasal polarity of brain endothelial cells - PMC

1 day ago WEB Oct 6, 2015  · The membrane localization of Par proteins is established and maintained by a system of reciprocal exclusion 119,120,128 (Figure 3(a)): aPKC, which forms a complex …

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SWATH-Based Comprehensive Determination of the Localization …

2 days ago WEB Dec 16, 2021  · The purpose of this study was to develop a method to comprehensively determine the localization of apical and basolateral membrane proteins, using a …

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Trafficking to the Apical and Basolateral Membranes in Polar ...

1 week ago WEB The Na,K-ATPase localizes to the apical membranes of cells of the retinal pigment epithelium (RPE) 113 – 116 and the choroid plexus. 117 – 120 Although these cells …

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VPS34-dependent control of apical membrane function of

1 week ago WEB Nov 29, 2022  · The metabolic function of the proximal tubule (PT) controls metabolic, kidney, and cardiovascular disease (18–27).Of 180 liters of primary urine every day, the …

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Molecular and functional profiling of apical versus basolateral …

2 weeks ago WEB Feb 16, 2021  · Of note, production of sEV from the apical membrane was significantly more abundant compared with the basolateral membrane for both normal and …

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Vectorial targeting of apical and basolateral plasma membrane …

1 day ago WEB Polarized confluent monolayers (2000 omega.cm2), grown on polycarbonate filter chambers, were pulsed with radioactive methionine/cysteine and, at different times of …

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Distinct Apical and Basolateral Membrane Requirements for …

1 day ago WEB Jan 1, 2009  · Second, during the early stage (i.e., phase 1 and 2 responses to outward bowing) the apical and basolateral membranes of the umbrella cell may have discrete …

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